Targeting the PyMT Oncogene to Diverse Mammary Cell Populations Enhances Tumor Heterogeneity and Generates Rare Breast Cancer Subtypes

Human breast cancer is a heterogeneous disease composed of different histologies and molecular subtypes, many of which are not replicated in animal models. Here, we report a mouse model of breast cancer that generates unique tumor histologies including tubular, adenosquamous, and lipid-rich carcinom...

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Main Authors: Smith, Brittni A., Shelton, Dawne N., Kieffer, Collin, Milash, Brett, Usary, Jerry, Perou, Charles M., Bernard, Philip S., Welm, Bryan E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: SAGE Publications 2012
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Original Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591097/
https://ncbi.nlm.nih.gov/pubmed/23486760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601913475359
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