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Ancestry Inference in Complex Admixtures via Variable-length Markov Chain Linkage Models

Inferring the ancestral origin of chromosomal segments in admixed individuals is key for genetic applications, ranging from analyzing population demographics and history, to mapping disease genes. Previous methods addressed ancestry inference by using either weak models of linkage disequilibrium, or...

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Hlavní autoři: Rodriguez, Jesse M., Bercovici, Sivan, Elmore, Megan, Batzoglou, Serafim
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590892/
https://ncbi.nlm.nih.gov/pubmed/23421795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2012.0088
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