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Ancestry Inference in Complex Admixtures via Variable-length Markov Chain Linkage Models

Inferring the ancestral origin of chromosomal segments in admixed individuals is key for genetic applications, ranging from analyzing population demographics and history, to mapping disease genes. Previous methods addressed ancestry inference by using either weak models of linkage disequilibrium, or...

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Detalhes bibliográficos
Main Authors: Rodriguez, Jesse M., Bercovici, Sivan, Elmore, Megan, Batzoglou, Serafim
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590892/
https://ncbi.nlm.nih.gov/pubmed/23421795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2012.0088
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