PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells.

The myeloperoxidase (MPO) and neutrophil elastase genes are expressed specifically in immature myeloid cells. The integrity of a polyomavirus enhancer core sequence, 5'-AACCACA-3', is critical to the activity of the murine MPO proximal enhancer. This element binds two species, myeloid nucl...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Nuchprayoon, I, Meyers, S, Scott, L M, Suzow, J, Hiebert, S, Friedman, A D
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1994
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359075/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8035830/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.8.5558
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