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Protein-tyrosine phosphatase activity of CD45 is activated by sequential phosphorylation by two kinases.

We describe a potential regulatory mechanism for the transmembrane protein-tyrosine phosphatase CD45. Phosphorylation on both tyrosine and serine residues in vitro results in an activation of CD45 specifically toward one artificial substrate but not another. The activation of these kinases appears t...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Stover, D R, Walsh, K A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 1994
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359072/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7518565/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.8.5523
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