Innovative estimation of survival using log-normal survival modelling on ACCENT database

BACKGROUND: The ACCENT database, with individual patient data for 20 898 patients from 18 colon cancer clinical trials, was used to support Food and Drug Administration (FDA) approval of 3-year disease-free survival as a surrogate for 5-year overall survival. We hypothesised substantive differences...

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Detalhes bibliográficos
Main Authors: Chapman, J W, O'Callaghan, C J, Hu, N, Ding, K, Yothers, G A, Catalano, P J, Shi, Q, Gray, R G, O'Connell, M J, Sargent, D J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590670/
https://ncbi.nlm.nih.gov/pubmed/23385733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.34
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