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Chromatin Structure in Telomere Dynamics
The establishment of a specific nucleoprotein structure, the telomere, is required to ensure the protection of chromosome ends from being recognized as DNA damage sites. Telomere shortening below a critical length triggers a DNA damage response that leads to replicative senescence. In normal human s...
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| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Frontiers Media S.A.
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3590461/ https://ncbi.nlm.nih.gov/pubmed/23471416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00046 |
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