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Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor.

We analyzed the binding site(s) for Grb2 on the epidermal growth factor (EGF) receptor (EGFR), using cell lines overexpressing EGFRs containing various point and deletion mutations in the carboxy-terminal tail. Results of co-immunoprecipitation experiments suggest that phosphotyrosines Y-1068 and Y-...

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Udgivet i:Mol Cell Biol
Principais autores: Batzer, A G, Rotin, D, Ureña, J M, Skolnik, E Y, Schlessinger, J
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359038/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7518560/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.8.5192-5201.1994
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