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Nonlinear Optical Imaging for Sensitive Detection of Crystals in Bulk Amorphous Powders

The primary aim of this study was to evaluate the utility of second-order nonlinear imaging of chiral crystals (SONICC) to quantify crystallinity in drug–polymer blends, including solid dispersions. Second harmonic generation (SHG) can potentially exhibit scaling with crystallinity between linear an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KESTUR, UMESH S., WANAPUN, DUANGPORN, TOTH, SCOTT J., WEGIEL, LINDSAY A., SIMPSON, GARTH J., TAYLOR, LYNNE S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590305/
https://ncbi.nlm.nih.gov/pubmed/22847843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23280
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