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Nonlinear Optical Imaging for Sensitive Detection of Crystals in Bulk Amorphous Powders
The primary aim of this study was to evaluate the utility of second-order nonlinear imaging of chiral crystals (SONICC) to quantify crystallinity in drug–polymer blends, including solid dispersions. Second harmonic generation (SHG) can potentially exhibit scaling with crystallinity between linear an...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3590305/ https://ncbi.nlm.nih.gov/pubmed/22847843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23280 |
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