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Direct interaction between STAT3 and EIF2AK2 controls fatty acid-induced autophagy
A chemical screen designed to identify novel inducers of autophagy led to the discovery that signal transducer and activator of transcription 3 (STAT3) inhibitors can potently stimulate the autophagic flux. Although STAT3 is best known as a pro-inflammatory and oncogenic transcription factor, mechan...
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| Auteurs principaux: | , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3590262/ https://ncbi.nlm.nih.gov/pubmed/23221979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22910 |
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