Direct interaction between STAT3 and EIF2AK2 controls fatty acid-induced autophagy

A chemical screen designed to identify novel inducers of autophagy led to the discovery that signal transducer and activator of transcription 3 (STAT3) inhibitors can potently stimulate the autophagic flux. Although STAT3 is best known as a pro-inflammatory and oncogenic transcription factor, mechan...

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Hlavní autoři: Niso-Santano, Mireia, Shen, Shensi, Adjemian, Sandy, Malik, Shoaib Ahmad, Mariño, Guillermo, Lachkar, Sylvie, Senovilla, Laura, Kepp, Oliver, Galluzzi, Lorenzo, Maiuri, Maria Chiara, Kroemer, Guido
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
Autophagic Punctum
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590262/
https://ncbi.nlm.nih.gov/pubmed/23221979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22910
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