Interaction of the Human Adenovirus Proteinase with Its 11-Amino Acid Cofactor pVIc

The interaction of the human adenovirus proteinase (AVP) and AVP–NA complexes with the 11-amino acid cofactor pVIc was characterized. The equilibrium dissociation constant for the binding of pVIc to AVP was 4.4 μM. The binding of AVP to 12-mer single-stranded DNA decreased the K(d) for the binding o...

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Bibliographic Details
Main Authors: Baniecki, Mary Lynn, McGrath, William J., McWhirter, Sarah M., Li, Caroline, Toledo, Diana L., Pellicena, Patricia, Barnard, Dale L., Thorn, Kurt S., Mangel, Walter F.
Format: Artigo
Language:Inglês
Published: 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590020/
https://ncbi.nlm.nih.gov/pubmed/11591154
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