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Limiting multiple sclerosis related axonopathy by blocking Nogo receptor and CRMP-2 phosphorylation

Multiple sclerosis involves demyelination and axonal degeneration of the central nervous system. The molecular mechanisms of axonal degeneration are relatively unexplored in both multiple sclerosis and its mouse model, experimental autoimmune encephalomyelitis. We previously reported that targeting...

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Bibliographische Detailangaben
Hauptverfasser: Petratos, Steven, Ozturk, Ezgi, Azari, Michael F., Kenny, Rachel, Young Lee, Jae, Magee, Kylie A., Harvey, Alan R., McDonald, Courtney, Taghian, Kasra, Moussa, Leon, Mun Aui, Pei, Siatskas, Christopher, Litwak, Sara, Fehlings, Michael G., Strittmatter, Stephen M., Bernard, Claude C. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589918/
https://ncbi.nlm.nih.gov/pubmed/22544872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws100
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