Plexina2 and CRMP2 Signaling Complex Is Activated by Nogo-A-Liganded Ngr1 to Restrict Corticospinal Axon Sprouting after Trauma

After brain or spinal cord trauma, interaction of Nogo-A with neuronal NgR1 limits regenerative axonal sprouting and functional recovery. Cellular signaling by lipid-anchored NgR1 requires a coreceptor but the relevant partner in vivo is not clear. Here, we examined proteins enriched in NgR1 immunop...

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Vydáno v:J Neurosci
Hlavní autoři: Sekine, Yuichi, Algarate, Percy T., Cafferty, William B.J., Strittmatter, Stephen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6788813/
https://ncbi.nlm.nih.gov/pubmed/30804090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2996-18.2019
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