Intraovarian transplantation of primordial follicles fails to rescue chemotherapy injured ovaries

Busulfan and cyclophosphamide (B/C)-treated mice exhibited a marked increase in apoptosis and a concomitant decrease in the ovarian weight. Histological and RT-PCR analysis indicate that the period of germ cell depletion in the B/C-treated ovaries coincides with decreased expression of genes Figla,...

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Main Authors: Park, Mi-Ryung, Choi, Yun-Jung, Kwon, Deug-Nam, Park, Chankyu, Bui, Hong-Thuy, Gurunathan, Sangiliyandi, Cho, Ssang-Goo, Song, Hyuk, Seo, Han Geuk, Min, Gyesik, Kim, Jin-Hoi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589785/
https://ncbi.nlm.nih.gov/pubmed/23463338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01384
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