Rapamycin ameliorates chitosan nanoparticle-induced developmental defects of preimplantation embryos in mice

Chitosan nanoparticles (CSNPs) are used as drug or gene delivery vehicles. However, a detailed understanding of the effects of CSNPs on embryonic development remains obscure. Here, we show that CSNPs can be internalized into mouse blastocysts, such as the zona pellucida, the perivitelline space, and...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Choi, Yun-Jung, Gurunathan, Sangiliyandi, Kim, DaSom, Jang, Hyung Seok, Park, Woo-Jin, Cho, Ssang-Goo, Park, Chankyu, Song, Hyuk, Seo, Han Geuk, Kim, Jin-Hoi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342693/
https://ncbi.nlm.nih.gov/pubmed/27463007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10813
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