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Enhancement of tumor immunotherapy by deletion of the A(2A) adenosine receptor
The A(2A) adenosine receptor plays a critical and non-redundant role in suppressing inflammation at sites of hypoxia and tissue damage. The tumor microenvironment has high levels of adenosine as a result of hypoxia and ectopic expression of enzymes responsible for the generation of extracellular ade...
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Hauptverfasser: | , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Springer-Verlag
2011
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3589752/ https://ncbi.nlm.nih.gov/pubmed/22116345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-1155-7 |
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