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Something in the Air: Hyperoxic Conditioning of the Tumor Microenvironment for Enhanced Immunotherapy

Recent clinical trials in cancer therapy have demonstrated unprecedented responses through blockade of CTLA-4 and PD-1 immune checkpoint pathways. In a provocative recent paper in Science Translational Medicine, Hatfield and colleagues demonstrate the ability of supplemental oxygen to act as a novel...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Leone, Robert D., Horton, Maureen R., Powell, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696011/
https://ncbi.nlm.nih.gov/pubmed/25873169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.03.014
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