The non-coding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells

The long non-coding RNA MALAT1, also known as MALAT-1 or NEAT2, is a highly conserved nuclear ncRNA and a predictive marker for metastasis development in lung cancer. To uncover its functional importance, we developed a MALAT1 knockout model in human lung tumor cells by genomically integrating RNA d...

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Autori principali: Gutschner, Tony, Hämmerle, Monika, Eißmann, Moritz, Hsu, Jeff, Kim, Youngsoo, Hung, Gene, Revenko, Alexey, Arun, Gayatri, Stentrup, Marion, Groß, Matthias, Zörnig, Martin, MacLeod, A. Robert, Spector, David L., Diederichs, Sven
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589741/
https://ncbi.nlm.nih.gov/pubmed/23243023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2850
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