Comparison of Direct Sequencing, PNA Clamping-Real Time Polymerase Chain Reaction, and Pyrosequencing Methods for the Detection of EGFR Mutations in Non-small Cell Lung Carcinoma and the Correlation with Clinical Responses to EGFR Tyrosine Kinase Inhibitor Treatment

BACKGROUND: The aims of this study were to evaluate the abilities of direct sequencing (DS), peptide nucleic acid (PNA) clamping, and pyrosequencing methods to detect epidermal growth factor receptor (EGFR) mutations in formalin-fixed paraffin-embedded (FFPE) non-small cell lung carcinoma (NSCLC) sa...

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Detalhes bibliográficos
Main Authors: Lee, Hyun Ju, Xu, Xianhua, Kim, Hyojin, Jin, Yan, Sun, Pingli, Kim, Ji Eun, Chung, Jin-Haeng
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Pathologists and The Korean Society for Cytopathology 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589609/
https://ncbi.nlm.nih.gov/pubmed/23483646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4132/KoreanJPathol.2013.47.1.52
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