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The Impact of 3′UTR Variants on Differential Expression of Candidate Cancer Susceptibility Genes

Variants in regulatory regions are predicted to play an important role in disease susceptibility of common diseases. Polymorphisms mapping to microRNA (miRNA) binding sites have been shown to disrupt the ability of miRNAs to target genes resulting in differential mRNA and protein expression. Skin tu...

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Hlavní autoři: Skeeles, Laura E., Fleming, Jessica L., Mahler, Kimberly L., Toland, Amanda Ewart
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589377/
https://ncbi.nlm.nih.gov/pubmed/23472213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058609
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