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IL-23 Induces Atopic Dermatitis-Like Inflammation Instead of Psoriasis-Like Inflammation in CCR2-Deficient Mice

Psoriasis is an immune-mediated chronic inflammatory skin disease, characterized by epidermal hyperplasia and infiltration of leukocytes into the dermis and epidermis. IL-23 is expressed in psoriatic skin, and IL-23 injected into the skin of mice produces IL-22-dependent dermal inflammation and acan...

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Detalhes bibliográficos
Main Authors: Bromley, Shannon K., Larson, Ryan P., Ziegler, Steven F., Luster, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589369/
https://ncbi.nlm.nih.gov/pubmed/23472158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058196
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