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TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis

Atopic dermatitis (AD) and psoriasis are driven by alternate type 2 and type 17 immune responses, but some proteins might be critical to both diseases. Here we show that a deficiency of the TNF superfamily molecule TWEAK (TNFSF12) in mice results in defective maintenance of AD-specific T helper type...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sidler, Daniel, Wu, Ping, Herro, Rana, Claus, Meike, Wolf, Dennis, Kawakami, Yuko, Kawakami, Toshiaki, Burkly, Linda, Croft, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493595/
https://ncbi.nlm.nih.gov/pubmed/28530223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15395
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