Observer bias in randomized clinical trials with measurement scale outcomes: a systematic review of trials with both blinded and nonblinded assessors

BACKGROUND: Clinical trials are commonly done without blinded outcome assessors despite the risk of bias. We wanted to evaluate the effect of nonblinded outcome assessment on estimated effects in randomized clinical trials with outcomes that involved subjective measurement scales. METHODS: We conduc...

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Autori principali: Hróbjartsson, Asbjørn, Thomsen, Ann Sofia Skou, Emanuelsson, Frida, Tendal, Britta, Hilden, Jørgen, Boutron, Isabelle, Ravaud, Philippe, Brorson, Stig
Natura: Artigo
Lingua:Inglês
Pubblicazione: Canadian Medical Association 2013
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589328/
https://ncbi.nlm.nih.gov/pubmed/23359047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/cmaj.120744
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