Observer bias in randomized clinical trials with measurement scale outcomes: a systematic review of trials with both blinded and nonblinded assessors

BACKGROUND: Clinical trials are commonly done without blinded outcome assessors despite the risk of bias. We wanted to evaluate the effect of nonblinded outcome assessment on estimated effects in randomized clinical trials with outcomes that involved subjective measurement scales. METHODS: We conduc...

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Detalhes bibliográficos
Main Authors: Hróbjartsson, Asbjørn, Thomsen, Ann Sofia Skou, Emanuelsson, Frida, Tendal, Britta, Hilden, Jørgen, Boutron, Isabelle, Ravaud, Philippe, Brorson, Stig
Formato: Artigo
Idioma:Inglês
Publicado em: Canadian Medical Association 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589328/
https://ncbi.nlm.nih.gov/pubmed/23359047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/cmaj.120744
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