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Strong activation of bile acid-sensitive ion channel (BASIC) by ursodeoxycholic acid

Bile acid-sensitive ion channel (BASIC) is a member of the DEG/ENaC gene family of unknown function. Rat BASIC (rBASIC) is inactive at rest. We have recently shown that cholangiocytes, the epithelial cells lining the bile ducts, are the main site of BASIC expression in the liver and identified bile...

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Bibliografiske detaljer
Main Authors: Wiemuth, Dominik, Sahin, Hacer, Lefèvre, Cathérine M.T., Wasmuth, Hermann E., Gründer, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589280/
https://ncbi.nlm.nih.gov/pubmed/23064163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.22406
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