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Preclinical Evaluation of An Anti-HCV miRNA Cluster for Treatment of HCV Infection
We developed a strategy to treat hepatitis C virus (HCV) infection by replacing five endogenous microRNA (miRNA) sequences of a natural miRNA cluster (miR-17–92) with sequences that are complementary to the HCV genome. This miRNA cluster (HCV-miR-Cluster 5) is delivered to cells using adeno-associat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3589168/ https://ncbi.nlm.nih.gov/pubmed/23295950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.247 |
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