Caricamento...

AAV-mediated Overexpression of Human α7 Integrin Leads to Histological and Functional Improvement in Dystrophic Mice

Duchenne muscular dystrophy (DMD) is a severe muscle disease caused by mutations in the DMD gene, with loss of its gene product, dystrophin. Dystrophin helps link integral membrane proteins to the actin cytoskeleton and stabilizes the sarcolemma during muscle activity. We investigated an alternative...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Heller, Kristin N, Montgomery, Chrystal L, Janssen, Paul ML, Clark, K Reed, Mendell, Jerry R, Rodino-Klapac, Louise R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589167/
https://ncbi.nlm.nih.gov/pubmed/23319059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.281
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !