PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population

Proprotein convertase subtilisin-like/kexin type 9 (PCSK9) is a protein involved in LDL-cholesterol metabolism. The single-nucleotide polymorphism (SNP) rs11591147 has been associated with lower LDL-cholesterol and a lower risk of coronary heart disease. Because PCSK9 has high affinity to the LDL re...

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Autores principales: Postmus, Iris, Trompet, Stella, de Craen, Anton J. M., Buckley, Brendan M., Ford, Ian, Stott, David J., Sattar, Naveed, Slagboom, P. Eline, Westendorp, Rudi G. J., Jukema, J. Wouter
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2013
Materias:
Patient-Oriented and Epidemiological Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588880/
https://ncbi.nlm.nih.gov/pubmed/23300213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M033969
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