Non-Homologous End-Joining Pathway Associated with Occurrence of Myocardial Infarction: Gene Set Analysis of Genome-Wide Association Study Data

PURPOSE: DNA repair deficiencies have been postulated to play a role in the development and progression of cardiovascular disease (CVD). The hypothesis is that DNA damage accumulating with age may induce cell death, which promotes formation of unstable plaques. Defects in DNA repair mechanisms may t...

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主要な著者: Verschuren, Jeffrey J. W., Trompet, Stella, Deelen, Joris, Stott, David J., Sattar, Naveed, Buckley, Brendan M., Ford, Ian, Heijmans, Bastiaan T., Guchelaar, Henk-Jan, Houwing-Duistermaat, Jeanine J., Slagboom, P. Eline, Jukema, J. Wouter
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574159/
https://ncbi.nlm.nih.gov/pubmed/23457540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056262
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