Non-Homologous End-Joining Pathway Associated with Occurrence of Myocardial Infarction: Gene Set Analysis of Genome-Wide Association Study Data

PURPOSE: DNA repair deficiencies have been postulated to play a role in the development and progression of cardiovascular disease (CVD). The hypothesis is that DNA damage accumulating with age may induce cell death, which promotes formation of unstable plaques. Defects in DNA repair mechanisms may t...

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Detalhes bibliográficos
Main Authors: Verschuren, Jeffrey J. W., Trompet, Stella, Deelen, Joris, Stott, David J., Sattar, Naveed, Buckley, Brendan M., Ford, Ian, Heijmans, Bastiaan T., Guchelaar, Henk-Jan, Houwing-Duistermaat, Jeanine J., Slagboom, P. Eline, Jukema, J. Wouter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574159/
https://ncbi.nlm.nih.gov/pubmed/23457540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056262
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