Non-Homologous End-Joining Pathway Associated with Occurrence of Myocardial Infarction: Gene Set Analysis of Genome-Wide Association Study Data

PURPOSE: DNA repair deficiencies have been postulated to play a role in the development and progression of cardiovascular disease (CVD). The hypothesis is that DNA damage accumulating with age may induce cell death, which promotes formation of unstable plaques. Defects in DNA repair mechanisms may t...

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Main Authors: Verschuren, Jeffrey J. W., Trompet, Stella, Deelen, Joris, Stott, David J., Sattar, Naveed, Buckley, Brendan M., Ford, Ian, Heijmans, Bastiaan T., Guchelaar, Henk-Jan, Houwing-Duistermaat, Jeanine J., Slagboom, P. Eline, Jukema, J. Wouter
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574159/
https://ncbi.nlm.nih.gov/pubmed/23457540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056262
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