Novel common and rare genetic determinants of paraoxonase activity: FTO, SERPINA12, and ITGAL

HDL-associated paraoxonase 1 (PON1) activity is associated with cardiovascular and other human diseases. As the role of genetic variants outside of the PON gene cluster on PON1 activity is unknown, we sought to identify common and rare variants in such loci. We typed 33,057 variants on the CVD chip...

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Detalhes bibliográficos
Main Authors: Kim, Daniel S., Burt, Amber A., Crosslin, David R., Robertson, Peggy D., Ranchalis, Jane E., Boyko, Edward J., Nickerson, Deborah A., Furlong, Clement E., Jarvik, Gail P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Patient-Oriented and Epidemiological Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588879/
https://ncbi.nlm.nih.gov/pubmed/23160181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P033266
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