Novel gene-by-environment interactions: APOB and NPC1L1 variants affect the relationship between dietary and total plasma cholesterol

Cardiovascular disease (CVD) is the leading cause of death in developed countries. Plasma cholesterol level is a key risk factor in CVD pathogenesis. Genetic and dietary variation both influence plasma cholesterol; however, little is known about dietary interactions with genetic variants influencing...

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Autores principales: Kim, Daniel S., Burt, Amber A., Ranchalis, Jane E., Jarvik, Ella R., Rosenthal, Elisabeth A., Hatsukami, Thomas S., Furlong, Clement E., Jarvik, Gail P.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2013
Materias:
Patient-Oriented and Epidemiological Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622343/
https://ncbi.nlm.nih.gov/pubmed/23482652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P035238
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