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Complementation of a capsule-deficient mutation of Cryptococcus neoformans restores its virulence.
Capsule formation plays a significant role in the pathogenicity of Cryptococcus neoformans. To study the molecular basis of capsule synthesis, the capsule-deficient phenotype of a mutant strain was complemented by transformation. A plasmid rescued from the resulting Cap+ transformant complemented a...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
1994
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC358863/ https://ncbi.nlm.nih.gov/pubmed/8007987 |
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