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The second capsule gene of cryptococcus neoformans, CAP64, is essential for virulence.

The extracellular polysaccharide capsule produced by Cryptococcus neoformans is essential for its pathogenicity. We have isolated and characterized a gene, (AP64, which is required for capsule formation. An encapsulated strain created by complementation of the cap64 mutation produced fatal infection...

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Autores principales: Chang, Y C, Penoyer, L A, Kwon-Chung, K J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1996
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC174025/
https://ncbi.nlm.nih.gov/pubmed/8675296
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