Tyrosine 569 in the c-Fms juxtamembrane domain is essential for kinase activity and macrophage colony-stimulating factor-dependent internalization.

The receptor (Fms) for macrophage colony-stimulating factor (M-CSF) is a member of the tyrosine kinase class of growth factor receptors. It maintains survival, stimulates growth, and drives differentiation of the macrophage lineage of hematopoietic cells. Fms accumulates on the cell surface and beco...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Myles, G M, Brandt, C S, Carlberg, K, Rohrschneider, L R
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358857/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8007983/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.7.4843-4854.1994
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