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Tyrosine 569 in the c-Fms juxtamembrane domain is essential for kinase activity and macrophage colony-stimulating factor-dependent internalization.

The receptor (Fms) for macrophage colony-stimulating factor (M-CSF) is a member of the tyrosine kinase class of growth factor receptors. It maintains survival, stimulates growth, and drives differentiation of the macrophage lineage of hematopoietic cells. Fms accumulates on the cell surface and beco...

詳細記述

保存先:
書誌詳細
出版年:Mol Cell Biol
主要な著者: Myles, G M, Brandt, C S, Carlberg, K, Rohrschneider, L R
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 1994
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358857/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8007983/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.7.4843-4854.1994
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