Expression of mutant eukaryotic initiation factor 2 alpha subunit (eIF-2 alpha) reduces inhibition of guanine nucleotide exchange activity of eIF-2B mediated by eIF-2 alpha phosphorylation.

The inhibition of protein synthesis that occurs upon phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (eIF-2 alpha) at serine 51 correlates with reduced guanine nucleotide exchange activity of eIF-2B in vivo and inhibition of eIF-2B activity in vitro, although it is not known i...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Ramaiah, K V, Davies, M V, Chen, J J, Kaufman, R J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358826/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8007958/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.7.4546-4553.1994
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