Remarkable Role of Indoleamine 2,3-Dioxygenase and Tryptophan Metabolites in Infectious Diseases: Potential Role in Macrophage-Mediated Inflammatory Diseases

Indoleamine 2,3-dioxygenase 1 (IDO1), the L-tryptophan-degrading enzyme, plays a key role in the immunomodulatory effects on several types of immune cells. Originally known for its regulatory function during pregnancy and chronic inflammation in tumorigenesis, the activity of IDO1 seems to modify th...

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Main Authors: Murakami, Yuki, Hoshi, Masato, Imamura, Yukio, Arioka, Yuko, Yamamoto, Yasuko, Saito, Kuniaki
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2013
Assuntos:
Review Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588179/
https://ncbi.nlm.nih.gov/pubmed/23476103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/391984
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