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Expression of a peptide inhibitor of protein phosphatase 1 increases phosphorylation and activity of CREB in NIH 3T3 fibroblasts.

We have examined the activity and phosphorylation state of the cyclic AMP (cAMP) response element binding factor (CREB) in intact NIH 3T3 cells following microinjection of expression plasmids encoding regulatory proteins of type 1 (PP1) and 2A (PP2A) serine/threonine-specific protein phosphatases. C...

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Udgivet i:Mol Cell Biol
Principais autores: Alberts, A S, Montminy, M, Shenolikar, S, Feramisco, J R
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358811/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7516466/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.7.4398-4407.1994
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