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Expression of a peptide inhibitor of protein phosphatase 1 increases phosphorylation and activity of CREB in NIH 3T3 fibroblasts.

We have examined the activity and phosphorylation state of the cyclic AMP (cAMP) response element binding factor (CREB) in intact NIH 3T3 cells following microinjection of expression plasmids encoding regulatory proteins of type 1 (PP1) and 2A (PP2A) serine/threonine-specific protein phosphatases. C...

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Publicat a:Mol Cell Biol
Autors principals: Alberts, A S, Montminy, M, Shenolikar, S, Feramisco, J R
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1994
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358811/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7516466/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.7.4398-4407.1994
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