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Effects of mutant Ran/TC4 proteins on cell cycle progression.

Ran/TC4, a member of the RAS gene superfamily, encodes an abundant nuclear protein that binds and hydrolyzes GTP. Transient expression of a Ran/TC4 mutant protein deficient in GTP hydrolysis blocked DNA replication, suggesting a role for Ran/TC4 in the regulation of cell cycle progression. To test t...

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Publicat a:Mol Cell Biol
Autors principals: Ren, M, Coutavas, E, D'Eustachio, P, Rush, M G
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358787/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8196659/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.6.4216-4224.1994
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