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Arp2/3 complex ATP hydrolysis promotes lamellipodial actin network disassembly but is dispensable for assembly
We examined the role of ATP hydrolysis by the Arp2/3 complex in building the leading edge of a cell by studying the effects of hydrolysis defects on the behavior of the complex in the lamellipodial actin network of Drosophila S2 cells and in a reconstituted, in vitro, actin-based motility system. In...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The Rockefeller University Press
2013
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587832/ https://ncbi.nlm.nih.gov/pubmed/23439681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201211069 |
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