GPD1, which encodes glycerol-3-phosphate dehydrogenase, is essential for growth under osmotic stress in Saccharomyces cerevisiae, and its expression is regulated by the high-osmolarity glycerol response pathway.

The yeast Saccharomyces cerevisiae responds to osmotic stress, i.e., an increase in osmolarity of the growth medium, by enhanced production and intracellular accumulation of glycerol as a compatible solute. We have cloned a gene encoding the key enzyme of glycerol synthesis, the NADH-dependent cytos...

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Pubblicato in:Mol Cell Biol
Autori principali: Albertyn, J, Hohmann, S, Thevelein, J M, Prior, B A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1994
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Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358779/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8196651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.6.4135
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