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Analysis of the selectivity filter of the voltage-gated sodium channel Na(v)Rh
NaChBac is a bacterial voltage-gated sodium (Na(v)) channel that shows sequence similarity to voltage-gated calcium channels. To understand the ion-permeation mechanism of Na(v) channels, we combined molecular dynamics simulation, structural biology and electrophysiological approaches to investigate...
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| Главные авторы: | , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587708/ https://ncbi.nlm.nih.gov/pubmed/23247626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.173 |
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