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Structure–activity relationship studies of naphthol AS-E and its derivatives as anticancer agents by inhibiting CREB-mediated gene transcription

CREB (cyclic AMP-response element binding protein) is a downstream transcription factor of a multitude of signaling pathways emanating from receptor tyrosine kinases or G-protein coupled receptors. CREB is not activated until it is phosphorylated at Ser133 and its subsequent binding to CREB-binding...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Li, Bingbing X., Yamanaka, Kinrin, Xiao, Xiangshu
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587690/
https://ncbi.nlm.nih.gov/pubmed/23102993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.09.056
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