Simvastatin Ameliorates Cauda Equina Compression Injury in a Rat Model of Lumbar Spinal Stenosis

Lumbar spinal stenosis (LSS) is the leading cause of morbidity and mortality worldwide. LSS pathology is associated with secondary injury caused by inflammation, oxidative damage and cell death. Apart from laminectomy, pharmacological therapy targeting secondary injury is limited. Statins are FDA-ap...

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Hlavní autoři: Shunmugavel, Anandakumar, Martin, Marcus M., Khan, Mushfiquddin, Copay, Anne G., Subach, Brian R., Schuler, Thomas C., Singh, Inderjit
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587651/
https://ncbi.nlm.nih.gov/pubmed/23188522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-012-9419-3
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