Simvastatin Ameliorates Cauda Equina Compression Injury in a Rat Model of Lumbar Spinal Stenosis

Lumbar spinal stenosis (LSS) is the leading cause of morbidity and mortality worldwide. LSS pathology is associated with secondary injury caused by inflammation, oxidative damage and cell death. Apart from laminectomy, pharmacological therapy targeting secondary injury is limited. Statins are FDA-ap...

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Main Authors: Shunmugavel, Anandakumar, Martin, Marcus M., Khan, Mushfiquddin, Copay, Anne G., Subach, Brian R., Schuler, Thomas C., Singh, Inderjit
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587651/
https://ncbi.nlm.nih.gov/pubmed/23188522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-012-9419-3
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