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ΔNp63α utilizes multiple mechanisms to repress transcription in squamous cell carcinoma cells

ΔNp63α is a potent oncogene in squamous cell carcinomas (SCCs) and a pro-proliferative factor expressed by basal epithelial cells. ΔNp63α functions both as a transcriptional repressor and activator, but it is not clear how these activities contribute to its oncogenic potential. ΔNp63α was proposed t...

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Библиографические подробности
Главные авторы: Gallant-Behm, Corrie L., Espinosa, Joaquín M.
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587441/
https://ncbi.nlm.nih.gov/pubmed/23324337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23593
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