Chimeric IgH-TCRα/δ translocations in T lymphocytes mediated by RAG

Translocations involving the T cell receptor alpha/delta (TCRα/δ) chain locus, which bring oncogenes in the proximity of the TCRα enhancer, are one of the hallmark features of human T cell malignancies from ataxia telangiectasia (AT) and non-AT patients. These lesions are frequently generated by the...

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Detalhes bibliográficos
Main Authors: Callén, Elsa, Bunting, Sam, Huang, Ching-Yu, Difilippantonio, Michael J., Wong, Nancy, Khor, Bernard, Mahowald, Grace, Kruhlak, Michael J., Ried, Thomas, Sleckman, Barry P., Nussenzweig, André
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2009
Assuntos:
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587430/
https://ncbi.nlm.nih.gov/pubmed/19556863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.8.15.9085
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