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Effects of ACE inhibition and ANG II stimulation on renal Na-Cl cotransporter distribution, phosphorylation, and membrane complex properties

The renal distal tubule Na-Cl cotransporter (NCC) reabsorbs <10% of the filtered Na(+) but is a key control point for blood pressure regulation by angiotensin II (ANG II), angiotensin-converting enzyme inhibitors (ACEI), and thiazide diuretics. This study aimed to determine whether NCC phosphoryl...

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Autors principals: Lee, Donna H., Maunsbach, Arvid B., Riquier-Brison, Anne D., Nguyen, Mien T. X., Fenton, Robert A., Bachmann, Sebastian, Yu, Alan S., McDonough, Alicia A.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587378/
https://ncbi.nlm.nih.gov/pubmed/23114965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00287.2012
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