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Hexamethylene diisocyanate (HDI) vapor reactivity with glutathione and subsequent transfer to human albumin

INTRODUCTION: Airway fluid glutathione (GSH) reactivity with inhaled vapors of diisocyanate, a common occupational allergen, is postulated to be a key step in exposure-induced asthma pathogenesis. METHODS: A mixed (vapor/liquid) phase exposure system was used to model the in vivo reactivity of inhal...

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Autors principals: Wisnewski, Adam V., Mhike, Morgen, Hettick, Justin M., Liu, Jian, Siegel, Paul D.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587365/
https://ncbi.nlm.nih.gov/pubmed/23178851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2012.11.013
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